![]() Here’s what should go in each of these sections: ![]() Google Docs can be helpful for maintaining a single version of the manuscript, but citation software often doesn’t play well with Google Docs (whereas most software options can automatically update citation changes in Word). Decide from the beginning what word processing software you’ll use (Word, Google Docs, etc.). Use Endnote, Reference Manager, Mendeley, or other citation software to start inserting references to go with bullets. This depends on the journal, but typically, and with minor variations: Introduction, Methods, Results, Discussion. Generate a bulleted outline of the major points for each section of the manuscript. ![]() Write bulleted captions for the figures/tables, including a title that explains the key finding for each figure/table, an explanation of experimental groups and associated symbols/labels, and details on biological and technical replicates and statements (such as “one of four representative experiments are shown.”) This will form the basis of your Results section. Gather your proposed figures and tables in a sequence that tells a story. Everything else will be spun around this. Write down your hypothesis/research question. Involve your principal investigator (PI) early and throughout the process. Here’s some thoughts on how to approach writing manuscripts based on original biomedical research. It’s hard work, but planning and organization helps. I’ve had the privilege of writing a few manuscripts in my research career to date, and helping trainees write them.
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